Created in the fifteenth century, the monastery was abolished in the nineteenth century switching to private hands. The set of buildings has undergone extensive renovation and expansion between the fifteenth and twentieth centuries. Adapted for some time as palatial residence of the Dukes of Bragança, São Marcos is presently under the tutelage of the University of Coimbra. The church is classified as a National Monument, highlighted by a set tomb dating from the fifteenth and sixteenth centuries, designed by the sculptor Diogo Pires-o-Moço.